Functionalization of thiocrown ethers containing the thioacetal unit
نویسندگان
چکیده
منابع مشابه
Reversible chemoselective tagging and functionalization of methionine containing peptides.
Reagents were developed to allow chemoselective tagging of methionine residues in peptides and polypeptides, subsequent bioorthogonal functionalization of the tags, and cleavage of the tags when desired. This methodology can be used for triggered release of therapeutic peptides, or release of tagged protein digests from affinity columns.
متن کاملFunctionalization of hexakis methanofullerene malonate crown-ethers: promising octahedral building blocks for molecular networks.
Hexaazido and hexaiodo macrocyclic methanofullerenes undergo high-yielding sixfold click reactions or sixfold Heck, Sonogashira and Suzuki cross-coupling reactions, respectively, to yield all organic building blocks for higher molecular architectures.
متن کاملConstruction of nitrogen-containing heterocycles by C-H bond functionalization.
Nitrogen heterocycles are abundant in natural products and pharmaceuticals. An emerging interest among synthetic chemists is to use C-H functionalization to construct the nitrogen-containing core of these heterocycles. The following article will provide a brief overview of this concept with respect to the type of C-H bond functionalized.
متن کاملStorable palladacycles for selective functionalization of alkyne-containing proteins.
We report the facile preparation of palladacycles as storable arylpalladium(II) reagents from acetanilides via cyclopalladation. The palladacycles exhibit good stability in PBS buffer and are capable of functionalizing a metabolically encoded HPG-containing protein, thus providing a new type of biocompatible organometallic reagent for selectively functionalizing the alkyne-encoded proteins.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Tetrahedron Letters
سال: 1998
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(98)01308-2